At first it's just Jews--then everyone. People are leaving their families to survive. Sam's wife, Claire, is already stricken and near death. In a year or two, as she grows into adulthood, their daughter, Esther, too, will become a victim. Sam and Claire decide to leave Esther on her own, hoping a "cure" will miraculously appear. Sam's car is waved off the road at a government-run laboratory where horrific tests are being conducted to create non-lethal speech. Throngs bang on the doors to be subject volunteers; they're all carried out half-dead. When Sam realizes what's going on, he makes a desperate escape, vowing that if he dies it will be with his family, the only refuge of sanity and love.
Ben Marcus's nightmarish vision is both completely alien and frighteningly familiar.